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Do Men Lose Weight Quicker Than Women?

Do Men Lose Weight Quicker Than Women?

A new analysis of clinical trials of Mounjaro (tirzepatide) has shown some very interesting findings that contrast greatly with a lot of prior knowledge, and misbeliefs, about gendered differences in weight loss. Let's dive into these new insights and explore what it means for your weight loss journey.



So, what did they find? 


A recent analysis of clinical trials for Mounjaro included 4,677 obese adults, and brought to light the following new gender disparities in weight loss:


Overall, in all these studies, Mounjaro demonstrated statistically significant reductions in body weight compared with placebo. However, there was a large discrepancy according to gender:


- Women lost between 11.5% to 27.6% of body weight.


- Men lost 8.8% to 18.9% of their body weight



Challenging Perceived Views


These are especially interesting findings, as these results seem to contradict what we have typically understood with regards to gender and weight loss. Have you ever started a weight loss journey with your partner and just can’t seem to understand why he’s shedding pounds and you’re the same size? Too often, women have been told we’re ‘not trying hard enough’ or seen as ‘lazy’, when there actually are biological factors at play. For instance, Polycystic Ovary Syndrome can make it harder to achieve, and stay at a healthy weight. Typically, research has indicated that men lose weight more quickly than women. Let's explore why:


  1. Muscle Mass: Generally, men possess more lean muscle mass than women. Muscle tissue, compared to fat tissue, utilises more calories at rest; hence, this predisposes men to a higher metabolic rate.

  1. Testosterone: Testosterones are more in men, and they help their bodies gain muscle and burn fat more effectively.

  1. Body Composition: Generally speaking, men have more muscle mass and less fat compared to women. This results in greater initial losses when starting a weight loss journey. 


Why is it different with Mounjaro?


The results from the study of Mounjaro are intriguing, as they reflect weight lost amongst women more than men; a finding opposite of what might have been expected. Although more studies will be required to understand this completely, it follows on the complexity of weight loss and how new medications can affect different body types differently.



What can we take from these findings?


  1. Individualised Strategies: One size does not fit all in weight management. What works best may vary not just between genders but between individuals. Don’t compare yourself to others and what progress they’re making, you are your own person. 

  1. Evolving Understanding: Our knowledge about weight loss is still evolving. New groundbreaking medications, such as Mounjaro, may offer different and more targeted results compared to traditional methods.

  1. Long-term Perspective: While initial weight loss rates may vary, it is the long-term results that truly count. If you want long-term sustainable results, you need to figure out what works best for you. 

  1. Overall approach: Weight management is a lot more than the use of medication. Diet, exercise, and behavioural changes all play an important role. Weight loss should be a holistic approach.


Looking Ahead 


Weight management is dynamic and an ever-evolving science. What works best for you may depend on a variety of factors beyond just gender. As Mounjaro becomes increasingly used for obesity treatment, including its recent approval by the NHS in England, we anticipate that a number of data and insights will continue to emerge. 


We're committed to being at the forefront of these developments to ensure you have access to the most effective evidence-based care. Remember, everyone is different when it comes to weight loss. Here at HANX, we will take you through every step of the way, feeding in approaches that best suit your needs and goals. 


Want to know more about Mounjaro, or one of our other, options for weight management? Start your consultation today and find out if you’re eligible for the programme. 


Want more?

  • Is it harder to lose weight if you have PCOS? Our in-house expert shares all.
Weight gain in menopause is common - and often difficult to manage. Learn more.

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